The efficacy of oral acyclovir 400 mg twice daily in suppressing frequently relapsing genital herpes simplex was evaluated in an open multicenter study.
The prolonged use of acyclovir was extremely well tolerated, and treatment efficacy was sustained through successive studies. Recurrences in eight patients with ...
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Long-term suppression of severe recurrent genital herpes simplex infections with oral acyclovir: a dose-titration study. S Kroon, C S Petersen, L P Andersen ...
A double-blind, placebo-controlled study was undertaken to evaluate the long-term efficacy and safety of oral acyclovir suppressive therapy over a 1-year period ...
... genital herpes lesions after one year of daily or episodic suppressive acyclovir therapy was discontinued. Median number of days to first recurrence while not.
Because of the decreased risk for recurrences and shedding, suppressive therapy for HSV-1 genital herpes should be reserved for those with frequent recurrences.
131 patients with frequently recurring genital herpes were treated for 1 year with reducing doses of oral acyclovir. The time to first recurrence in ...
Suppressive Therapy of Recurrent HSV-1 Genital Herpes. Recurrences are less frequent after the first episode of HSV-1 genital herpes ...
It is concluded that long-term suppression with acyclovir is safe and effective for patients with recurrent genital herpes. Article info.
Molin L, Ruhnek-Forsbeck M & Svennerholm B (1991) One year acyclovir suppression of frequently recurring genital herpes: a study of efficacy, safety, virus ...